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KMID : 0378019640070010115
New Medical Journal
1964 Volume.7 No. 1 p.115 ~ p.117
The Effect of X-irradiation on Distribution of Orally Administered Co^60 Vitamin B_12 in Rats



Abstract
Present study describes the effect of X-irradiation on the distribution of orally administered ,¢¥radioac= ive Vitamin B12 in rats.
The rats were irradiated 900 r ¢¥X-ray¢¥ on ¢¥ whole body and were administrated COD Vitamin BI2 (48.3 /xmg.,-0.1 #c.) as well as in "unirradiated.control group.
The liver.¢¥ kidney, spleen and femur were removed 3 days after Vitamin B12 administration, -and the contents of Co60 Vitamin B12 were measured.
The results are as follows :
1) The distribution of Vitamin B12 showed a tendency of increase in irradiated rats¢¥ liver and kidney
2) The contents of Co60 Vitamin B12 were slightly less in irradiated rats¢¥ spleen and markedly less in irradiated rats¢¥ femur than in control group.
3) The results shows that 900 r whole body X-irradiation has no effect on the absorption of Vitamin B12 from the intestine.
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